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Symbol
Name
ID

Tlr4
toll-like receptor 4
MGI:96824

Phenotype annotations related to respiratory system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Recurrent pharyngitis	Pleural effusion	Asthma	Bronchoconstriction	Abnormal pleura morphology	Pleuritis	Airway hyperresponsiveness	Chronic pulmonary obstruction	Cough
Disease(s) Associated with TLR4	Recurrent pharyngitis	Pleural effusion	Asthma	Bronchoconstriction	Abnormal pleura morphology	Pleuritis	Airway hyperresponsiveness	Chronic pulmonary obstruction	Cough
asthma
atopic dermatitis
chronic obstructive pulmonary disease
familial mediterranean fever
temporal arteritis

Mouse Phenotypes

respiratory system phenotype

enlarged lung

pulmonary edema

lung inflammation

abnormal respiratory system morphology

abnormal pulmonary alveolar duct morphology

dilated pulmonary alveolar duct

abnormal pulmonary alveolus morphology

abnormal pulmonary elastic fiber morphology

abnormal respiratory system physiology

abnormal airway responsiveness

increased lung compliance

Availability

Mouse Genotype

Tlr4^Lps-d/Tlr4^Lps-d

Tlr4^lps-del/Tlr4^lps-del

Tlr4^tm1Aki/Tlr4^tm1Aki

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23